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Gene Modification Uncovers the Secrets Behind the Longevity of ‘Immortal’ Jellyfish

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Gene Modification May Explain How “Immortal” Jellyfish Live So Long

  • Researchers have made a breakthrough in understanding the aging process by studying transposable elements (TEs) in DNA.
  • A specific process called the Piwi-piRNA pathway helps control TEs and has been observed in cells that don’t age, such as cancer stem cells and the “immortal jellyfish.”
  • By strengthening this pathway in worms, the researchers were able to significantly extend their lifespan.
  • Controlling the activity of TEs can slow down the aging process, indicating their crucial role in aging.
  • Gene Modification May Explain How “Immortal” Jellyfish Live So Long

    Researchers from Eötvös Loránd University have made an exciting breakthrough in understanding how we age. They focused on transposable elements (TEs) in DNA, which can destabilize the genetic code and lead to aging. By studying the Piwi-piRNA pathway, which controls TEs, they found that strengthening this pathway in worms extended their lifespan. This research provides experimental proof of the relationship between TEs and aging, and opens up possibilities for further study.

    Understanding Transposable Elements and Aging

    Transposable elements (TEs) are parts of DNA that can move around in our genetic code. When these TEs move too much, they can destabilize the genetic code and contribute to the aging process. Researchers from Eötvös Loránd University have focused on the Piwi-piRNA pathway, which helps control TEs. By studying this pathway, they have discovered that strengthening it in worms can significantly extend their lifespan. This research provides valuable insights into the role of TEs in aging and opens up new possibilities for further study.

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