NYU Langone Health will co-lead the NIH-funded effort to understand the long-term effects of SARS-CoV-2 infection.

NYU Langone Health will co-lead the NIH-funded effort to understand the long-term effects of SARS-CoV-2 infection.

“We are grateful to the NIH for their support of this important mission, which is to better understand the long-term effects of SARS-CoV-2 infection, and to find new ways to avert a potentially profound public health crisis,” says Stuart Katz, MD, director of NYU Langone Health’s Heart Failure Program and principal investigator for the PASC CSC. Congress provided $1.15 billion in funding over four years for NIH to support research into the prolonged health consequences of SARS-CoV-2 infection in December of 2020. According to the NIH, the PASC Consortium of the initiative will seek to answer several basic questions:

What does the spectrum of recovery from SARS-CoV-2 infection look like across the population?
How many people continue to have symptoms of COVID-19, or even develop new symptoms, after acute SARS-CoV-2 infection?
What are the underlying biological causes of these prolonged symptoms?
What makes some people vulnerable to prolonged effects, but not others?
Does SARS-CoV-2 infection trigger changes in the body that increase the risk of other conditions, such as chronic heart or brain disorders? CONTACT: Gregory Williams, [email protected]

“Congratulation to these leaders, who were among the first to acknowledge the collective professional expertise and the technical skills made by countless NYU Langone collaborators in support of an initiative of this magnitude and importance to the health of our patients,” says Dafna Bar-Sagi, PhD, the Saul J. Farber Professor in the Department of Biochemistry & Molecular Pharmacology and Chief Scientific Officer at NYU Langone Health. SOURCE NYU Langone Health

The PASC CSC at NYU Langone Health (NIH funding no. 1OT2 HL161847) will be led by an interdisciplinary principal investigator team composed of senior faculty, including Katz; Leora Horwitz, MD, director, Center for Healthcare Innovation and Delivery Science (Co-Principal Investigator); and Andrea Troxel, ScD, director, Division of Biostatistics (Co-Principal Investigator). A central part of the PASC initiative will be the creation of the SARS-CoV-2 Recovery Cohort, comprising multiple patient groups to be followed over time. Studies of the Recovery Cohort will aim to characterize the long-term effects of infection in a diverse set of people and the trajectory of their symptoms over time. The initiative also will support studies from other data resources such as electronic health records and patient specimens to better understand the underlying mechanisms of PASC.

Source

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