Primary ovarian failure associated with an increased risk of osteoporosis

Primary ovarian failure associated with an increased risk of osteoporosis

CLEVELAND, Ohio (March 3, 2021) – Loss of estrogen after menopause is associated with rapid bone loss. A new study compared bone health outcomes in women with primary ovarian failure (POI) and early menopause with postmenopausal women of normal age to confirm the association between POI and osteoporosis. The results of the study are published online today in Menopause, the journal of the North American Menopause Society (NAMS).

Osteoporosis is a skeletal condition characterized by low bone mass and deterioration of bone tissue which leads to fragility and an increased risk of fracture. The wasting disease, which affects more women than men, is associated with significant morbidity and mortality in osteoporotic fractures, leading to an increased rate of institutionalization and risk of mortality.

Previous studies have suggested an association between osteoporosis and POI, which is the loss of ovarian function before the age of 40. This new study is however the first to be carried out on a larger scale, with more of 12,000 participants. This confirms the results of smaller studies that have demonstrated an association between POI and early menopause …

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